Portable spectral Doppler echocardiographic device: overcoming limitations

M-mode, Two-dimensional, Spectral Doppler and Tissue Doppler Echocardiographic Findings in 40 Healthy Pet Rabbits

Next to dogs and cats, rabbits are popular companion animals in the United Kingdom with 1.7 million kept as pets. Almost 60% of these rabbits are registered with a veterinary practice. The number of reported or anecdotal reports describing congenital or acquired cardiac diseases is increasing, which results in a growing demand to perform echocardiography in pet rabbits as clinical cases. Report...

Directed evolution: overcoming biology's limitations.

The field of directed, in vitro evolution uses biological machinery to develop nucleic acid and peptide oligomers that bind to molecular targets, some of which are important for therapeutic applications1,2. The advantage of this approach over traditional small molecule–based medicinal chemistry is based in part on the number of molecules that may be screened: in vitro evolution can screen upwar...

A Novel Portable Scissors-Type Fruit Picking Device

At present, the fruit picking in most countries still largely relies on manual operation. Manual fruit picking can protect the fruits from damage during the operation process. However, it is time-consuming and labor-intensive, and poses a potential safety risk to the workers while working at heights not reachable. Therefore, a variety of fruit picking machines and platforms have been developed ...

Portable Electroencephalogram Biofeedback Device

Overcoming current limitations in humanized mouse research.

Immunodeficient mice engrafted with human cells and tissues have provided an exciting alternative to in vitro studies with human tissues and nonhuman primates for the study of human immunobiology. A major breakthrough in the early 2000s was the introduction of a targeted mutation in the interleukin 2 (IL-2) receptor common gamma chain (IL2rg(null)) into mice that were already deficient in T and...